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Structure paper

TitleStructural basis for dual roles of Aar2p in U5 snRNP assembly.
Journal, issue, pagesGenes Dev., Vol. 27, Page 525-540, Year 2013
Publish dateDec 31, 2012 (structure data deposition date)
AuthorsWeber, G. / Cristao, V.F. / Santos, K.F. / Jovin, S.M. / Heroven, A.C. / Holton, N. / Luhrmann, R. / Beggs, J.D. / Wahl, M.C.
External linksGenes Dev. / PubMed:23442228
MethodsX-ray diffraction
Resolution2.0001 - 3.2046 Å
Structure data

PDB-4ilg:
Crystal structure of Aar2p in complex with the Prp8p RNaseH and Jab1/MPN domains
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

PDB-4ili:
Crystal structure of an Aar2p S253E phosphomimetic mutant protein
Method: X-RAY DIFFRACTION / Resolution: 3.2046 Å

PDB-4ilj:
Crystal structure of an Prp8p RNaseH W1911A mutant protein
Method: X-RAY DIFFRACTION / Resolution: 2.0001 Å

Chemicals

ChemComp-EPE:
4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID / pH buffer*YM

ChemComp-HOH:
WATER

Source
  • saccharomyces cerevisiae (brewer's yeast)
KeywordsSPLICING / U5 snRNP assembly / Aar2 / Prp8

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