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Structure paper

TitleStructure of the MST4 in Complex with MO25 Provides Insights into Its Activation Mechanism
Journal, issue, pagesStructure, Vol. 21, Page 449-461, Year 2013
Publish dateJul 6, 2012 (structure data deposition date)
AuthorsShi, Z. / Jiao, S. / Zhang, Z. / Ma, M. / Chen, C. / Wang, K. / Wang, H. / Wang, W. / Zhang, L. / Zhao, Y. / Zhou, Z.
External linksStructure / PubMed:23434407
MethodsX-ray diffraction
Resolution3.15 - 3.64 Å
Structure data

PDB-4fza:
Crystal structure of MST4-MO25 complex
Method: X-RAY DIFFRACTION / Resolution: 3.15 Å

PDB-4fzd:
Crystal structure of MST4-MO25 complex with WSF motif
Method: X-RAY DIFFRACTION / Resolution: 3.25 Å

PDB-4fzf:
Crystal structure of MST4-MO25 complex with DKI
Method: X-RAY DIFFRACTION / Resolution: 3.64 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

ChemComp-DKI:
5-AMINO-3-{[4-(AMINOSULFONYL)PHENYL]AMINO}-N-(2,6-DIFLUOROPHENYL)-1H-1,2,4-TRIAZOLE-1-CARBOTHIOAMIDE

Source
  • homo sapiens (human)
KeywordsSIGNALING PROTEIN/TRANSFERASE / Scaffold protein / Protein Ser/Thr kinase / ATP binding / SIGNALING PROTEIN-TRANSFERASE complex / SIGNALING PROTEIN/TRANSFERASE/INHIBITOR / SIGNALING PROTEIN-TRANSFERASE-INHIBITOR complex

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