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-Structure paper
Title | Design, synthesis and SAR of novel glucokinase activators. |
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Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 23, Page 2166-2171, Year 2013 |
Publish date | Jan 16, 2013 (structure data deposition date) |
![]() | Cheruvallath, Z.S. / Gwaltney, S.L. / Sabat, M. / Tang, M. / Feng, J. / Wang, H. / Miura, J. / Guntupalli, P. / Jennings, A. / Hosfield, D. ...Cheruvallath, Z.S. / Gwaltney, S.L. / Sabat, M. / Tang, M. / Feng, J. / Wang, H. / Miura, J. / Guntupalli, P. / Jennings, A. / Hosfield, D. / Lee, B. / Wu, Y. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 1.78 - 2.645 Å |
Structure data | ![]() PDB-4ise: ![]() PDB-4isf: ![]() PDB-4isg: |
Chemicals | ![]() ChemComp-GLC: ![]() ChemComp-1FW: ![]() ChemComp-IOD: ![]() ChemComp-HOH: ![]() ChemComp-1FX: ![]() ChemComp-1FY: |
Source |
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![]() | TRANSFERASE/TRANSFERASE ACTIVATOR / transferase/activator activity / glucose conversion to G6P / phosphorylation / TRANSFERASE-TRANSFERASE ACTIVATOR complex |