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-Structure paper
Title | Design of a superior cytokine antagonist for topical ophthalmic use. |
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Journal, issue, pages | Proc. Natl. Acad. Sci. USA, Vol. 110, Page 3913-3918, Year 2013 |
Publish date | Jul 25, 2012 (structure data deposition date) |
![]() | Hou, J. / Townson, S.A. / Kovalchin, J.T. / Masci, A. / Kiner, O. / Shu, Y. / King, B.M. / Schirmer, E. / Golden, K. / Thomas, C. ...Hou, J. / Townson, S.A. / Kovalchin, J.T. / Masci, A. / Kiner, O. / Shu, Y. / King, B.M. / Schirmer, E. / Golden, K. / Thomas, C. / Garcia, K.C. / Zarbis-Papastoitsis, G. / Furfine, E.S. / Barnes, T.M. |
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Methods | X-ray diffraction |
Resolution | 1.49 - 2.15 Å |
Structure data | ![]() PDB-4gaf: ![]() PDB-4gai: |
Chemicals | ![]() ChemComp-NAG: ![]() ChemComp-NA: ![]() ChemComp-HOH: |
Source |
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![]() | SIGNALING PROTEIN / IL-1beta / IL-1Ra / IL-1R1 / IL-1 signaling / Beta-trefoil |