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Structure paper

TitleBapineuzumab captures the N-terminus of the Alzheimer's disease amyloid-beta peptide in a helical conformation.
Journal, issue, pagesSci Rep, Vol. 3, Page 1302-1302, Year 2013
Publish dateOct 12, 2012 (structure data deposition date)
AuthorsMiles, L.A. / Crespi, G.A. / Doughty, L. / Parker, M.W.
External linksSci Rep / PubMed:23416764
MethodsX-ray diffraction
Resolution2.204 Å
Structure data

PDB-4hix:
Crystal structure of a humanised 3D6 Fab bound to amyloid beta peptide
Method: X-RAY DIFFRACTION / Resolution: 2.204 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • mus musculus (house mouse)
KeywordsPROTEIN FIBRIL/Immune System / immunoglobulin / immunotherapy candidate / amyloid beta peptide / PROTEIN FIBRIL-Immune System complex

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