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Structure paper

TitleThe structural basis of actinomycin D-binding induces nucleotide flipping out, a sharp bend and a left-handed twist in CGG triplet repeats.
Journal, issue, pagesNucleic Acids Res., Vol. 41, Page 4284-4294, Year 2013
Publish dateOct 12, 2012 (structure data deposition date)
AuthorsLo, Y.S. / Tseng, W.H. / Chuang, C.Y. / Hou, M.H.
External linksNucleic Acids Res. / PubMed:23408860
MethodsX-ray diffraction
Resolution2.6 Å
Structure data

PDB-4hiv:
Structure of actinomycin D d(ATGCGGCAT) complex
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • streptomyces antibioticus (bacteria)
KeywordsDNA/ANTIBIOTIC / Double helix DNA / Nucleotide flipping-out / sharp kink / left-handed twist / CGG tripleat repeat / Neurological disease / DNA-ANTIBIOTIC complex

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