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Structure paper

TitleEfficient chemical synthesis of human complement protein C3a.
Journal, issue, pagesChem. Commun. (Camb. ), Vol. 49, Page 2356-2358, Year 2013
Publish dateNov 29, 2012 (structure data deposition date)
AuthorsGhassemian, A. / Wang, C.I. / Yau, M.K. / Reid, R.C. / Lewis, R.J. / Fairlie, D.P. / Alewood, P.F. / Durek, T.
External linksChem. Commun. (Camb. ) / PubMed:23407800
MethodsX-ray diffraction
Resolution2.14 Å
Structure data

PDB-4i6o:
Crystal structure of chemically synthesized human anaphylatoxin C3a
Method: X-RAY DIFFRACTION / Resolution: 2.14 Å

Chemicals

ChemComp-MPD:
(4S)-2-METHYL-2,4-PENTANEDIOL / precipitant*YM

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / disulfide-rich / alpha-helical bundle / drumstick / complement system / third component of complement (C3) / local inflammatory process mediator / smooth muscle contraction induction / vascular permeability increase / mast cell histamine release / C3a receptor / GPCR / extracellular / blood plasma

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