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Structure paper

TitleStructural basis for ion permeation mechanism in pentameric ligand-gated ion channels.
Journal, issue, pagesEmbo J., Vol. 32, Page 728-741, Year 2013
Publish dateOct 5, 2012 (structure data deposition date)
AuthorsSauguet, L. / Poitevin, F. / Murail, S. / Van Renterghem, C. / Moraga-Cid, G. / Malherbe, L. / Thompson, A.W. / Koehl, P. / Corringer, P.J. / Baaden, M. / Delarue, M.
External linksEmbo J. / PubMed:23403925
MethodsX-ray diffraction
Resolution2.4 - 3.5 Å
Structure data

PDB-4hfi:
The GLIC pentameric Ligand-Gated Ion Channel at 2.4 A resolution
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

PDB-4il4:
The pentameric ligand-gated ion channel GLIC in complex with Se-DDM
Method: X-RAY DIFFRACTION / Resolution: 3.3 Å

PDB-4il9:
The pentameric ligand-gated ion channel GLIC A237F in complex with bromide
Method: X-RAY DIFFRACTION / Resolution: 2.83 Å

PDB-4ila:
The pentameric ligand-gated ion channel GLIC A237F in complex with Cesium
Method: X-RAY DIFFRACTION / Resolution: 3.5 Å

PDB-4ilb:
The pentameric ligand-gated ion channel GLIC A237F in complex with Rubidium
Method: X-RAY DIFFRACTION / Resolution: 3.15 Å

PDB-4ilc:
The GLIC pentameric ligand-gated ion channel in complex with sulfates
Method: X-RAY DIFFRACTION / Resolution: 2.99 Å

Chemicals

ChemComp-ACT:
ACETATE ION

ChemComp-PLC:
DIUNDECYL PHOSPHATIDYL CHOLINE / phospholipid*YM

ChemComp-CL:
Unknown entry

ChemComp-NA:
Unknown entry

ChemComp-LMT:
DODECYL-BETA-D-MALTOSIDE / detergent*YM

ChemComp-HOH:
WATER

ChemComp-LSM:
dodecyl 4-O-alpha-D-glucopyranosyl-1-seleno-beta-D-glucopyranoside


ChemComp, No image

ChemComp-UNL:
Unknown ligand

ChemComp-BR:
BROMIDE ION

ChemComp-CS:
Unknown entry

ChemComp-RB:
RUBIDIUM ION

ChemComp-SO4:
SULFATE ION

Source
  • gloeobacter violaceus (bacteria)
KeywordsMEMBRANE PROTEIN / TRANSPORT PROTEIN / pentameric transmembrane channel / ion channel / pentameric ligand-gated ion channel / membrane

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