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-Structure paper
Title | Optimized S-Trityl-L-Cysteine-Based Inhibitors of Kinesin Spindle Protein with Potent in Vivo Antitumor Activity in Lung Cancer Xenograft Models. |
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Journal, issue, pages | J. Med. Chem., Vol. 56, Page 1878-, Year 2013 |
Publish date | Sep 22, 2012 (structure data deposition date) |
![]() | Good, J.A.D. / Wang, F. / Rath, O. / Kaan, H.Y.K. / Talapatra, S.K. / Podgorski, D. / Mackay, S.P. / Kozielski, F. |
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Methods | X-ray diffraction |
Resolution | 2.75 Å |
Structure data | ![]() PDB-4bbg: |
Chemicals | ![]() ChemComp-ADP: ![]() ChemComp-MG: ![]() ChemComp-CL: ![]() ChemComp-V02: ![]() ChemComp-HOH: |
Source |
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![]() | CELL CYCLE / MITOSIS / INHIBITOR |