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Structure paper

TitleStructure of the oncoprotein Rcl bound to three nucleotide analogues.
Journal, issue, pagesActa Crystallogr. ,Sect. D, Vol. 69, Page 247-255, Year 2013
Publish dateJul 4, 2012 (structure data deposition date)
AuthorsPadilla, A. / Amiable, C. / Pochet, S. / Kaminski, P.A. / Labesse, G.
External linksActa Crystallogr. ,Sect. D / PubMed:23385460
MethodsX-ray diffraction
Resolution1.79 - 2.44 Å
Structure data

PDB-4fyh:
Crystal structure of rcl with phospho-triciribine
Method: X-RAY DIFFRACTION / Resolution: 2.44 Å

PDB-4fyi:
Crystal structure of rcl with 6-cyclopentyl-AMP
Method: X-RAY DIFFRACTION / Resolution: 1.96 Å

PDB-4fyk:
Crystal structure of rcl with 5'-phiosphorothioate-adenosine
Method: X-RAY DIFFRACTION / Resolution: 1.79 Å

Chemicals

ChemComp-TR5:
5-methyl-1-(5-O-phosphono-beta-D-ribofuranosyl)-1,5-dihydro-1,4,5,6,8-pentaazaacenaphthylen-3-amine

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

ChemComp-6C6:
N-cyclopentyladenosine 5'-(dihydrogen phosphate)

ChemComp-SRA:
ADENOSINE -5'-THIO-MONOPHOSPHATE

Source
  • rattus norvegicus (Norway rat)
KeywordsHYDROLASE/INHIBITOR / Deoxyribonucleoside 5'-monophosphate N-glycosidase / HYDROLASE-INHIBITOR complex / HYDROLASE

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