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-Structure paper
Title | Development of Inhibitors of the PAS-B Domain of the HIF-2 alpha Transcription Factor |
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Journal, issue, pages | J. Med. Chem., Vol. 56, Page 1739-1747, Year 2013 |
Publish date | Aug 27, 2012 (structure data deposition date) |
![]() | Rogers, J.L. / Bayeh, L. / Scheuermann, T.H. / Longgood, J. / Key, J. / Naidoo, J. / Melito, L. / Shokri, C. / Frantz, D.E. / Bruick, R.K. ...Rogers, J.L. / Bayeh, L. / Scheuermann, T.H. / Longgood, J. / Key, J. / Naidoo, J. / Melito, L. / Shokri, C. / Frantz, D.E. / Bruick, R.K. / Gardner, K.H. / Macmillan, J.B. / Tambar, U.K. |
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Methods | X-ray diffraction |
Resolution | 1.72 Å |
Structure data | ![]() PDB-4gs9: |
Chemicals | ![]() ChemComp-0XB: ![]() ChemComp-PE8: ![]() ChemComp-HOH: |
Source |
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![]() | TRANSCRIPTION / PAS fold / protein-protein interactions / nucleus |