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Structure paper

TitleParamyxovirus V proteins disrupt the fold of the RNA sensor MDA5 to inhibit antiviral signaling.
Journal, issue, pagesScience, Vol. 339, Page 690-693, Year 2013
Publish dateNov 21, 2012 (structure data deposition date)
AuthorsMotz, C. / Schuhmann, K.M. / Kirchhofer, A. / Moldt, M. / Witte, G. / Conzelmann, K.K. / Hopfner, K.P.
External linksScience / PubMed:23328395
MethodsX-ray diffraction
Resolution2.293 Å
Structure data

PDB-4i1s:
Melanoma differentiation associated protein-5 Helicase domain complex with inhibitor Non-structural protein V
Method: X-RAY DIFFRACTION / Resolution: 2.293 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-HOH:
WATER

Source
  • sus scrofa (pig)
  • simian virus 5
KeywordsHydrolase/Hydrolase Inhibitor / SF2-ATPase / Helicase / Hydrolase-Hydrolase Inhibitor complex

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