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-Structure paper
Title | Discovery of a class of novel tankyrase inhibitors that bind to both the nicotinamide pocket and the induced pocket. |
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Journal, issue, pages | J. Med. Chem., Vol. 56, Page 1341-1345, Year 2013 |
Publish date | Dec 5, 2012 (structure data deposition date) |
![]() | Bregman, H. / Gunaydin, H. / Gu, Y. / Schneider, S. / Wilson, C. / DiMauro, E.F. / Huang, X. |
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Methods | X-ray diffraction |
Resolution | 2.4 Å |
Structure data | ![]() PDB-4i9i: |
Chemicals | ![]() ChemComp-ZN: ![]() ChemComp-1DY: ![]() ChemComp-HOH: |
Source |
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![]() | TRANSFERASE/TRANSFERASE INHIBITOR / tankyrase / PARP / inhibitor / TRANSFERASE-TRANSFERASE INHIBITOR complex |