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TitleA novel transition-state analogue for lysozyme, 4-O-beta-tri-N-acetylchitotriosyl moranoline, provided evidence supporting the covalent glycosyl-enzyme intermediate.
Journal, issue, pagesJ. Biol. Chem., Vol. 288, Page 6072-6082, Year 2013
Publish dateOct 23, 2012 (structure data deposition date)
AuthorsOgata, M. / Umemoto, N. / Ohnuma, T. / Numata, T. / Suzuki, A. / Usui, T. / Fukamizo, T.
External linksJ. Biol. Chem. / PubMed:23303182
MethodsX-ray diffraction
Resolution1.19 Å
Structure data

PDB-4hp0:
Crystal Structure of Hen Egg White Lysozyme in complex with GN3-M
Method: X-RAY DIFFRACTION / Resolution: 1.19 Å

PDB-4hpi:
Crystal Structure of Hen Egg White Lysozyme complex with GN2-M
Method: X-RAY DIFFRACTION / Resolution: 1.19 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • gallus gallus (chicken)
KeywordsHYDROLASE/HYDROLASE INHIBITOR / Lysozyme / Carbohydrate / HYDROLASE-HYDROLASE INHIBITOR complex

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