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TitleDiscovery of a chemical probe for the L3MBTL3 methyllysine reader domain.
Journal, issue, pagesNat. Chem. Biol., Vol. 9, Page 184-191, Year 2013
Publish dateJun 14, 2012 (structure data deposition date)
AuthorsJames, L.I. / Barsyte-Lovejoy, D. / Zhong, N. / Krichevsky, L. / Korboukh, V.K. / Herold, J.M. / MacNevin, C.J. / Norris, J.L. / Sagum, C.A. / Tempel, W. ...James, L.I. / Barsyte-Lovejoy, D. / Zhong, N. / Krichevsky, L. / Korboukh, V.K. / Herold, J.M. / MacNevin, C.J. / Norris, J.L. / Sagum, C.A. / Tempel, W. / Marcon, E. / Guo, H. / Gao, C. / Huang, X.P. / Duan, S. / Emili, A. / Greenblatt, J.F. / Kireev, D.B. / Jin, J. / Janzen, W.P. / Brown, P.J. / Bedford, M.T. / Arrowsmith, C.H. / Frye, S.V.
External linksNat. Chem. Biol. / PubMed:23292653
MethodsX-ray diffraction
Resolution2.55 Å
Structure data

PDB-4fl6:
Crystal structure of the complex of the 3-MBT repeat domain of L3MBTL3 and UNC1215
Method: X-RAY DIFFRACTION / Resolution: 2.55 Å

Chemicals

ChemComp-UWN:
[2-(phenylamino)benzene-1,4-diyl]bis{[4-(pyrrolidin-1-yl)piperidin-1-yl]methanone}

ChemComp-UNX:
Unknown entry

Source
  • homo sapiens (human)
KeywordsTRANSCRIPTION / Structural Genomics Consortium / SGC / chromatin modification / transcription repression / MBT repeat

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