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-Structure paper
Title | Lead optimization of novel p53-MDM2 interaction inhibitors possessing dihydroimidazothiazole scaffold |
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Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 23, Page 728-732, Year 2013 |
Publish date | Oct 16, 2012 (structure data deposition date) |
![]() | Miyazaki, M. / Naito, H. / Sugimoto, Y. / Kawato, H. / Okayama, T. / Shimizu, H. / Kitagawa, M. / Seki, T. / Fukutake, S. / Aonuma, M. / Soga, T. |
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Methods | X-ray diffraction |
Resolution | 2.8 Å |
Structure data | ![]() PDB-3vzv: |
Chemicals | ![]() ChemComp-VZV: |
Source |
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![]() | LIGASE/LIGASE INHIBITOR / Ubiquitin-protein ligase E3 Mdm2 / p53 / LIGASE-LIGASE INHIBITOR complex |