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Structure paper

TitleRegulating the ARNT/TACC3 Axis: Multiple Approaches to Manipulating Protein/Protein Interactions with Small Molecules.
Journal, issue, pagesAcs Chem. Biol., Vol. 8, Page 626-635, Year 2013
Publish dateApr 17, 2012 (structure data deposition date)
AuthorsGuo, Y. / Partch, C.L. / Key, J. / Card, P.B. / Pashkov, V. / Patel, A. / Bruick, R.K. / Wurdak, H. / Gardner, K.H.
External linksAcs Chem. Biol. / PubMed:23240775
MethodsX-ray diffraction
Resolution1.6 Å
Structure data

PDB-4eq1:
Crystal Structure of the ARNT PAS-B homodimer
Method: X-RAY DIFFRACTION / Resolution: 1.6 Å

Chemicals

ChemComp-PE5:
3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL / precipitant*YM

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSCRIPTION / Per-ARNT-Sim / transcription regulation / homodimer / transcription factor / DNA-binding / HIF1 / HIF2 / Ahr

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