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TitleDivergent synthesis of 48 heparan sulfate-based disaccharides and probing the specific sugar-fibroblast growth factor-1 interaction
Journal, issue, pagesJ. Am. Chem. Soc., Vol. 134, Page 20722-20727, Year 2012
Publish dateOct 27, 2011 (structure data deposition date)
AuthorsHu, Y.-P. / Zhong, Y.-Q. / Chen, Z.-G. / Chen, C.-Y. / Shi, Z. / Zulueta, M.M.L. / Ku, C.-C. / Lee, P.-Y. / Wang, C.-C. / Hung, S.-C.
External linksJ. Am. Chem. Soc. / PubMed:23240683
MethodsX-ray diffraction
Resolution2.34 - 2.8 Å
Structure data

PDB-3ud7:
Crystal Structure Analysis of FGF1-Disaccharide(NI21) complexes
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

PDB-3ud8:
Crystal Structure Analysis of FGF1-Disaccharide(NI22) complex
Method: X-RAY DIFFRACTION / Resolution: 2.37 Å

PDB-3ud9:
Crystal Structure Analysis of FGF1-Disaccharide(NI23) complex
Method: X-RAY DIFFRACTION / Resolution: 2.34 Å

PDB-3uda:
Crystal Structure Analysis of FGF1-Disaccharide(NI24) complex
Method: X-RAY DIFFRACTION / Resolution: 2.51 Å

Chemicals

ChemComp-PO4:
PHOSPHATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHORMONE / Heparin/Heparan sulfate Binding

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