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-Structure paper
Title | Ternary complex structures of human farnesyl pyrophosphate synthase bound with a novel inhibitor and secondary ligands provide insights into the molecular details of the enzyme's active site closure. |
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Journal, issue, pages | Bmc Struct. Biol., Vol. 12, Page 32-32, Year 2012 |
Publish date | Sep 18, 2012 (structure data deposition date) |
![]() | Park, J. / Lin, Y.S. / De Schutter, J.W. / Tsantrizos, Y.S. / Berghuis, A.M. |
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Methods | X-ray diffraction |
Resolution | 2.02 - 2.04 Å |
Structure data | ![]() PDB-4h5c: ![]() PDB-4h5d: ![]() PDB-4h5e: |
Chemicals | ![]() ChemComp-YS4: ![]() ChemComp-PO4: ![]() ChemComp-MG: ![]() ChemComp-HOH: ![]() ChemComp-POP: ![]() ChemComp-IPR: |
Source |
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![]() | TRANSFERASE/TRANSFERASE INHIBITOR / Transferase / TRANSFERASE-TRANSFERASE INHIBITOR complex |