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Structure paper

TitleThe structural basis of direct glucocorticoid-mediated transrepression.
Journal, issue, pagesNat. Struct. Mol. Biol., Vol. 20, Page 53-58, Year 2013
Publish dateOct 18, 2012 (structure data deposition date)
AuthorsHudson, W.H. / Youn, C. / Ortlund, E.A.
External linksNat. Struct. Mol. Biol. / PubMed:23222642
MethodsX-ray diffraction
Resolution1.902 - 2.549 Å
Structure data

PDB-4hn5:
GR DNA Binding Domain - TSLP nGRE Complex
Method: X-RAY DIFFRACTION / Resolution: 1.902 Å

PDB-4hn6:
GR DNA Binding Domain R460D/D462R - TSLP nGRE Complex
Method: X-RAY DIFFRACTION / Resolution: 2.549 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • synthetic construct (others)
KeywordsTranscription/DNA / Glucocorticoid receptor / steroid receptors / DNA / nGRE / Repression / Transcription / Transcription-DNA complex

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