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Structure paper

TitleCowchock syndrome is associated with a mutation in apoptosis-inducing factor.
Journal, issue, pagesAm. J. Hum. Genet., Vol. 91, Page 1095-1102, Year 2012
Publish dateMay 27, 2012 (structure data deposition date)
AuthorsRinaldi, C. / Grunseich, C. / Sevrioukova, I.F. / Schindler, A. / Horkayne-Szakaly, I. / Lamperti, C. / Landoure, G. / Kennerson, M.L. / Burnett, B.G. / Bonnemann, C. ...Rinaldi, C. / Grunseich, C. / Sevrioukova, I.F. / Schindler, A. / Horkayne-Szakaly, I. / Lamperti, C. / Landoure, G. / Kennerson, M.L. / Burnett, B.G. / Bonnemann, C. / Biesecker, L.G. / Ghezzi, D. / Zeviani, M. / Fischbeck, K.H.
External linksAm. J. Hum. Genet. / PubMed:23217327
MethodsX-ray diffraction
Resolution2.4 Å
Structure data

PDB-4fdc:
Crystal structure of the E493V mutant of human apoptosis inducing factor (AIF)
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

Chemicals

ChemComp-FAD:
FLAVIN-ADENINE DINUCLEOTIDE / FAD*YM

Source
  • homo sapiens (human)
KeywordsAPOPTOSIS / OXIDOREDUCTASE / Rossmann Fold / mitochondrion / APPOPTOSIS

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