+Search query
-Structure paper
Title | 3,6-Diamino-4-(2-Halophenyl)-2-Benzoylthieno(2,3-B) Pyridine-5-Carbonitriles are Selective Inhibitors of Plasmodium Falciparum Glycogen Synthase Kinase-3 (Pfgsk-3) |
---|---|
Journal, issue, pages | J. Med. Chem., Vol. 56, Page 264-, Year 2013 |
Publish date | Nov 27, 2012 (structure data deposition date) |
Authors | Fugel, W. / Oberholzer, A.E. / Gschloessl, B. / Dzikowski, R. / Pressburger, N. / Preu, L. / Pearl, L.H. / Baratte, B. / Ratin, M. / Okun, I. ...Fugel, W. / Oberholzer, A.E. / Gschloessl, B. / Dzikowski, R. / Pressburger, N. / Preu, L. / Pearl, L.H. / Baratte, B. / Ratin, M. / Okun, I. / Doerig, C. / Kruggel, S. / Lemcke, T. / Meijer, L. / Kunick, C. |
External links | J. Med. Chem. / PubMed:23214499 |
Methods | X-ray diffraction |
Resolution | 2.645 Å |
Structure data | PDB-3zdi: |
Chemicals | ChemComp-PO4: ChemComp-UGJ: ChemComp-HOH: |
Source |
|
Keywords | TRANSFERASE/PEPTIDE / TRANSFERASE-PEPTIDE COMPLEX / INSULIN PATHWAY / WNT SIGNALING PATHWAY / TRANSFERASE SERINE/THREONINE-PROTEIN KINASE / INHIBITOR |