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Structure paper

TitleCrystal Structures of Pseudomonas Aeruginosa Gim-1: Active-Site Plasticity in Metallo-Beta-Lactamases.
Journal, issue, pagesAntimicrob. Agents Chemother., Vol. 57, Page 848-, Year 2013
Publish dateOct 18, 2012 (structure data deposition date)
AuthorsBorra, P.S. / Samuelsen, O. / Spencer, J. / Walsh, T.R. / Lorentzen, M.S. / Leiros, H.-K.S.
External linksAntimicrob. Agents Chemother. / PubMed:23208706
MethodsX-ray diffraction
Resolution1.598 - 2.06 Å
Structure data

PDB-2ynt:
GIM-1-3Mol native. Crystal structures of Pseudomonas aeruginosa GIM- 1: active site plasticity in metallo-beta-lactamases
Method: X-RAY DIFFRACTION / Resolution: 1.598 Å

PDB-2ynu:
Apo GIM-1 with 2Mol. Crystal structures of Pseudomonas aeruginosa GIM-1: active site plasticity in metallo-beta-lactamases
Method: X-RAY DIFFRACTION / Resolution: 2.06 Å

PDB-2ynv:
Cys221 oxidized, Mono zinc GIM-1 - GIM-1-Ox. Crystal structures of Pseudomonas aeruginosa GIM-1: active site plasticity in metallo-beta- lactamases
Method: X-RAY DIFFRACTION / Resolution: 2.05 Å

PDB-2ynw:
GIM-1-2Mol native. Crystal structures of Pseudomonas aeruginosa GIM- 1: active site plasticity in metallo-beta-lactamases
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

ChemComp-MG:
Unknown entry

ChemComp-SO4:
SULFATE ION

Source
  • pseudomonas aeruginosa (bacteria)
KeywordsHYDROLASE / ANTIBIOTIC RESISTANCE / RESIDUE DETERMINANTS / LOOP DYNAMICS

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