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Title | Cyanobacterial Peptides as a Prototype for the Design of Potent beta-Secretase Inhibitors and the Development of Selective Chemical Probes for Other Aspartic Proteases |
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Journal, issue, pages | J. Med. Chem., Vol. 55, Page 10749-10765, Year 2012 |
Publish date | Nov 21, 2011 (structure data deposition date) |
![]() | Liu, Y. / Zhang, W. / Li, L. / Salvador, L.A. / Chen, T.T. / Chen, W.Y. / Felsenstein, K.M. / Ladd, T.B. / Price, A.R. / Golde, T.E. ...Liu, Y. / Zhang, W. / Li, L. / Salvador, L.A. / Chen, T.T. / Chen, W.Y. / Felsenstein, K.M. / Ladd, T.B. / Price, A.R. / Golde, T.E. / He, J. / Xu, Y.C. / Li, Y. / Luesch, H. |
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Methods | X-ray diffraction |
Resolution | 1.59 - 3.056 Å |
Structure data | ![]() PDB-3uqp: ![]() PDB-3uqr: ![]() PDB-4dv9: ![]() PDB-4dvf: ![]() PDB-4fgx: |
Chemicals | ![]() ChemComp-SO4: ![]() ChemComp-HOH: ![]() ChemComp-URE: ![]() ChemComp-PEG: |
Source |
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![]() | HYDROLASE/HYDROLASE INHIBITOR / HYDROLASE / HYDROLASE-HYDROLASE INHIBITOR complex |