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-Structure paper
Title | New 2-(Aryloxy)-3-phenylpropanoic Acids as Peroxisome Proliferator-Activated Receptor alpha/gamma Dual Agonists Able To Upregulate Mitochondrial Carnitine Shuttle System Gene Expression. |
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Journal, issue, pages | J. Med. Chem., Vol. 56, Page 60-72, Year 2013 |
Publish date | Mar 13, 2012 (structure data deposition date) |
![]() | Laghezza, A. / Pochetti, G. / Lavecchia, A. / Fracchiolla, G. / Faliti, S. / Piemontese, L. / Di Giovanni, C. / Iacobazzi, V. / Infantino, V. / Montanari, R. ...Laghezza, A. / Pochetti, G. / Lavecchia, A. / Fracchiolla, G. / Faliti, S. / Piemontese, L. / Di Giovanni, C. / Iacobazzi, V. / Infantino, V. / Montanari, R. / Capelli, D. / Tortorella, P. / Loiodice, F. |
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Methods | X-ray diffraction |
Resolution | 2.5 Å |
Structure data | ![]() PDB-4e4k: ![]() PDB-4e4q: |
Chemicals | ![]() ChemComp-RRG: ![]() ChemComp-HOH: ![]() ChemComp-RRH: |
Source |
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![]() | TRANSCRIPTION / bundle of alpha-helices and a small four-stranded beta-sheet / transcription factor |