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TitleHeterotrimeric G-protein Signaling Is Critical to Pathogenic Processes in Entamoeba histolytica.
Journal, issue, pagesPlos Pathog., Vol. 8, Page e1003040-e1003040, Year 2012
Publish dateJun 8, 2012 (structure data deposition date)
AuthorsBosch, D.E. / Kimple, A.J. / Muller, R.E. / Giguere, P.M. / Machius, M. / Willard, F.S. / Temple, B.R. / Siderovski, D.P.
External linksPlos Pathog. / PubMed:23166501
MethodsX-ray diffraction
Resolution2.62 Å
Structure data

PDB-4fid:
Crystal structure of a heterotrimeric G-Protein subunit from entamoeba histolytica, EHG-ALPHA-1
Method: X-RAY DIFFRACTION / Resolution: 2.62 Å

Chemicals

ChemComp-GDP:
GUANOSINE-5'-DIPHOSPHATE / GDP, energy-carrying molecule*YM

ChemComp-HOH:
WATER

Source
  • entamoeba histolytica (eukaryote)
KeywordsSIGNALING PROTEIN / RAS-LIKE DOMAIN / ALL-HELICAL DOMAIN / GTP BINDING / NUCLEOTIDE BINDING / TRANSDUCER / LIPOPROTEIN / REDUCTIVE METHYLATION

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