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-Structure paper
Title | Crystal Structures of HIV-1 Reverse Transcriptase with Picomolar Inhibitors Reveal Key Interactions for Drug Design. |
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Journal, issue, pages | J. Am. Chem. Soc., Vol. 134, Page 19501-19503, Year 2012 |
Publish date | Sep 17, 2012 (structure data deposition date) |
Authors | Frey, K.M. / Bollini, M. / Mislak, A.C. / Cisneros, J.A. / Gallardo-Macias, R. / Jorgensen, W.L. / Anderson, K.S. |
External links | J. Am. Chem. Soc. / PubMed:23163887 |
Methods | X-ray diffraction |
Resolution | 2.85 - 2.9 Å |
Structure data | PDB-4h4m: PDB-4h4o: |
Chemicals | ChemComp-494: ChemComp-EDO: ChemComp-HOH: ChemComp-506: |
Source |
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Keywords | Hydrolase/Hydrolase inhibitor / Polymerase / Transferase / Hydrolase/inhibitor / Hydrolase-Hydrolase inhibitor complex / Rnase |