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-Structure paper
Title | A Bacterial Glycosidase Enables Mannose-6-Phosphate Modification and Improved Cellular Uptake of Yeast-Produced Recombinant Human Lysosomal Enzymes. |
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Journal, issue, pages | Nat. Biotechnol., Vol. 30, Page 1225-, Year 2012 |
Publish date | Sep 29, 2010 (structure data deposition date) |
![]() | Tiels, P. / Baranova, E. / Piens, K. / De Visscher, C. / Pynaert, G. / Nerinckx, W. / Stout, J. / Fudalej, F. / Hulpiau, P. / Tannler, S. ...Tiels, P. / Baranova, E. / Piens, K. / De Visscher, C. / Pynaert, G. / Nerinckx, W. / Stout, J. / Fudalej, F. / Hulpiau, P. / Tannler, S. / Geysens, S. / Van Hecke, A. / Valevska, A. / Vervecken, W. / Remaut, H. / Callewaert, N. |
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Methods | X-ray diffraction |
Resolution | 2 - 2.09 Å |
Structure data | ![]() PDB-2xsg: ![]() PDB-4aq0: |
Chemicals | ![]() ChemComp-CA: ![]() ChemComp-B3P: ![]() ChemComp-GOL: ![]() ChemComp-HOH: ![]() ChemComp-DMJ: |
Source |
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![]() | HYDROLASE / MANNOSIDASE |