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-Structure paper
Title | Free-Wilson and Structural Approaches to Co-Optimising Human and Rodent Isoform Potency for 11Beta-Hydroxysteroid Dehydrogenase Type 1 (11Beta-Hsd1) Inhibitors |
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Journal, issue, pages | J. Med. Chem., Vol. 55, Page 10652-, Year 2012 |
Publish date | Sep 20, 2012 (structure data deposition date) |
![]() | Goldberg, F.W. / Leach, A.G. / Scott, J.S. / Snelson, W.L. / Groombridge, S.D. / Donald, C.S. / Bennett, S.N.L. / Bodin, C. / Morentin Gutierrez, P. / Gyte, A.C. |
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Methods | X-ray diffraction |
Resolution | 2.2 - 2.55 Å |
Structure data | ![]() PDB-4bb5: ![]() PDB-4bb6: |
Chemicals | ![]() ChemComp-NAP: ![]() ChemComp-HD2: ![]() ChemComp-HOH: ![]() ChemComp-HD1: ![]() ChemComp-CL: |
Source |
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![]() | OXIDOREDUCTASE / BHSD |