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TitleRoom-temperature X-ray diffraction studies of cisplatin and carboplatin binding to His15 of HEWL after prolonged chemical exposure.
Journal, issue, pagesActa Crystallogr. ,Sect. F, Vol. 68, Page 1300-1306, Year 2012
Publish dateJul 16, 2012 (structure data deposition date)
AuthorsTanley, S.W. / Schreurs, A.M. / Kroon-Batenburg, L.M. / Helliwell, J.R.
External linksActa Crystallogr. ,Sect. F / PubMed:23143236
MethodsX-ray diffraction
Resolution2 - 2.4 Å
Structure data

PDB-4g49:
Room temperature X-ray diffraction of cisplatin binding to HEWL in aqueous media after 15 months of crystal storage
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

PDB-4g4b:
Room temperature X-ray diffraction study of cisplatin binding to HEWL in DMSO media with NAG after 7 months of crystal storage
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

PDB-4g4c:
Room temperature X-ray diffraction study of carboplatin binding to HEWL in DMSO media after 13 months of crystal storage
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-4g4h:
100K X-ray diffraction study of carboplatin binding to HEWL in DMSO media after 13 months of crystal storage
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-CL:
Unknown entry

ChemComp-ACT:
ACETATE ION

ChemComp-CPT:
Cisplatin / medication, chemotherapy*YM

ChemComp-HOH:
WATER

ChemComp-DMS:
DIMETHYL SULFOXIDE / DMSO, precipitant*YM

ChemComp-QPT:
carboplatin / medication, chemotherapy*YM

Source
  • gallus gallus (chicken)
KeywordsHYDROLASE / cisplatin / carboplatin / aqueous media / DMSO media / omega scan data collection / capillaries

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