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TitleThe structure of (-)-kaitocephalin bound to the ligand binding domain of the (S)-alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)/glutamate receptor, GluA2.
Journal, issue, pagesJ. Biol. Chem., Vol. 287, Page 41007-41013, Year 2012
Publish dateSep 4, 2012 (structure data deposition date)
AuthorsAhmed, A.H. / Hamada, M. / Shinada, T. / Ohfune, Y. / Weerasinghe, L. / Garner, P.P. / Oswald, R.E.
External linksJ. Biol. Chem. / PubMed:23076153
MethodsX-ray diffraction
Resolution1.9634 Å
Structure data

PDB-4gxs:
Ligand binding domain of GluA2 (AMPA/glutamate receptor) bound to (-)-kaitocephalin
Method: X-RAY DIFFRACTION / Resolution: 1.9634 Å

Chemicals

ChemComp-0YS:
(5R)-2-[(1S,2R)-2-amino-2-carboxy-1-hydroxyethyl]-5-{(2S)-2-carboxy-2-[(3,5-dichloro-4-hydroxybenzoyl)amino]ethyl}-L-proline / neurotransmitter, antagonist*YM

ChemComp-ZN:
Unknown entry

ChemComp-HOH:
WATER

Source
  • rattus norvegicus (Norway rat)
KeywordsMEMBRANE PROTEIN / glutamate receptor / GluA2 / GluR2 / AMPA receptor / neurotransmitter receptor / (-)-kaitocephalin

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