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| Title | De Novo GTP Biosynthesis is Critical for Virulence of the Fungal Pathogen Cryptococcus Neoformans |
|---|---|
| Journal, issue, pages | Plos Pathog., Vol. 8, Page 2957-, Year 2012 |
| Publish date | Jan 15, 2012 (structure data deposition date) |
Authors | Morrow, C.A. / Valkov, E. / Stamp, A. / Chow, E.W.L. / Lee, I.R. / Wronski, A. / Williams, S.J. / Hill, J.M. / Djordjevic, J.T. / Kappler, U. ...Morrow, C.A. / Valkov, E. / Stamp, A. / Chow, E.W.L. / Lee, I.R. / Wronski, A. / Williams, S.J. / Hill, J.M. / Djordjevic, J.T. / Kappler, U. / Kobe, B. / Fraser, J.A. |
External links | Plos Pathog. / PubMed:23071437 |
| Methods | X-ray diffraction |
| Resolution | 2.2 Å |
| Structure data | ![]() PDB-4af0: |
| Chemicals | ![]() ChemComp-MOA: ![]() ChemComp-IMP: ![]() ChemComp-SO4: ![]() ChemComp-HOH: |
| Source |
|
Keywords | OXIDOREDUCTASE / GTP BIOSYNTHESIS / DRUG RESISTANCE |
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cryptococcus neoformans (Cryptococcus neoformans serotype A)
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