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Structure paper

TitleStructural and functional insights into the role of the N-terminal Mps1 TPR domain in the SAC (spindle assembly checkpoint).
Journal, issue, pagesBiochem. J., Vol. 448, Page 321-328, Year 2012
Publish dateSep 21, 2012 (structure data deposition date)
AuthorsThebault, P. / Chirgadze, D.Y. / Dou, Z. / Blundell, T.L. / Elowe, S. / Bolanos-Garcia, V.M.
External linksBiochem. J. / PubMed:23067341
MethodsX-ray diffraction
Resolution1.8 - 2.6 Å
Structure data

PDB-4h7x:
Crystal structure of the tetratricopeptide repeat (TPR) motif of human dual specificity protein kinase Mps1
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

PDB-4h7y:
Crystal structure of the tetratricopeptide repeat (TPR) motif of human dual specificity protein kinase Mps1
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

Chemicals

ChemComp-PB:
LEAD (II) ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / mitotic checkpoint kinase / chromosome instability / cancer / tetratricopeptide repeat (TPR) motif / mitotic checkpoint

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