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Structure paper

TitleThe structural biochemistry of Zucchini implicates it as a nuclease in piRNA biogenesis.
Journal, issue, pagesNature, Vol. 491, Page 279-283, Year 2012
Publish dateAug 6, 2012 (structure data deposition date)
AuthorsIpsaro, J.J. / Haase, A.D. / Knott, S.R. / Joshua-Tor, L. / Hannon, G.J.
External linksNature / PubMed:23064227
MethodsX-ray diffraction
Resolution1.75 - 2.1 Å
Structure data

PDB-4ggj:
Crystal structure of Zucchini from mouse (mZuc / PLD6 / MitoPLD)
Method: X-RAY DIFFRACTION / Resolution: 1.75 Å

PDB-4ggk:
Crystal structure of Zucchini from mouse (mZuc / PLD6 / MitoPLD) bound to tungstate
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-WO4:
TUNGSTATE(VI)ION

Source
  • mus musculus (house mouse)
KeywordsHYDROLASE / piRNA pathway / protein-RNA interactions / piRNA RNAi / HKD motif CCCH zinc finger / nuclease / nucleic acid binding / outer mitochondrial membrane / piRNA biogenesis / RNA interference / RNAi

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