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TitleCrystal structure of adenovirus E3-19K bound to HLA-A2 reveals mechanism for immunomodulation.
Journal, issue, pagesNat. Struct. Mol. Biol., Vol. 19, Page 1176-1181, Year 2012
Publish dateMar 14, 2012 (structure data deposition date)
AuthorsLi, L. / Muzahim, Y. / Bouvier, M.
External linksNat. Struct. Mol. Biol. / PubMed:23042604
MethodsX-ray diffraction
Resolution1.95 Å
Structure data

PDB-4e5x:
Crystal structure of a complex between the human adenovirus type 2 E3-19K protein and MHC class I molecule HLA-A2/Tax
Method: X-RAY DIFFRACTION / Resolution: 1.95 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • human adenovirus 6
  • human t-cell lymphotropic virus type 1 (african isolate)
KeywordsIMMUNE SYSTEM/TRANSCRIPTION / Ad2 E3-19K-HLA-A2 complex / unique tertiary structure / Adenovirus E3-19K / Immune evasion function / MHC class I molecule / Endoplasmic reticulum / IMMUNE SYSTEM-TRANSCRIPTION complex

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