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Structure paper

TitleStructure of a topoisomerase II-DNA-nucleotide complex reveals a new control mechanism for ATPase activity.
Journal, issue, pagesNat. Struct. Mol. Biol., Vol. 19, Page 1147-1154, Year 2012
Publish dateAug 3, 2012 (structure data deposition date)
AuthorsSchmidt, B.H. / Osheroff, N. / Berger, J.M.
External linksNat. Struct. Mol. Biol. / PubMed:23022727
MethodsX-ray diffraction
Resolution4.408 Å
Structure data

PDB-4gfh:
Topoisomerase II-DNA-AMPPNP complex
Method: X-RAY DIFFRACTION / Resolution: 4.408 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-ANP:
PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER / AMP-PNP, energy-carrying molecule analogue*YM

Source
  • saccharomyces cerevisiae (brewer's yeast)
KeywordsIsomerase/DNA / TOPOISOMERASE / PROTEIN-DNA COMPLEX / DNA SUPERCOILING / DNA REPLICATION / ATP-BINDING / DNA-BINDING / ISOMERASE / NUCLEOTIDE-BINDING / NUCLEUS / PHOSPHOPROTEIN / ISOMERASE-DNA COMPLEX

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