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TitleThe crystal structure of the Rv0301-Rv0300 VapBC-3 toxin-antitoxin complex from M. tuberculosis reveals a Mg(2+) ion in the active site and a putative RNA-binding site.
Journal, issue, pagesProtein Sci., Vol. 21, Page 1754-1767, Year 2012
Publish dateApr 28, 2009 (structure data deposition date)
AuthorsMin, A.B. / Miallau, L. / Sawaya, M.R. / Habel, J. / Cascio, D. / Eisenberg, D.
External linksProtein Sci. / PubMed:23011806
MethodsX-ray diffraction
Resolution1.49 Å
Structure data

PDB-3h87:
Rv0301 Rv0300 Toxin Antitoxin Complex from Mycobacterium tuberculosis
Method: X-RAY DIFFRACTION / Resolution: 1.49 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-MG:
Unknown entry

ChemComp-BME:
BETA-MERCAPTOETHANOL

ChemComp-IMD:
IMIDAZOLE

ChemComp-HOH:
WATER

Source
  • mycobacterium tuberculosis (bacteria)
KeywordsTOXIN/ANTITOXIN / toxin antitoxin complex / VapBC complex / RHH motif / structural genomics / tuberculosis / Integrated Center for Structure and Function Innovation / ISFI / TOXIN-ANTITOXIN COMPLEX / PSI-2 / Protein Structure Initiative

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