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-Structure paper
Title | Substrate-Selective Inhibition of Protein Kinase Pdk1 by Small Compounds that Bind to the Pif-Pocket Allosteric Docking Site. |
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Journal, issue, pages | Chem. Biol., Vol. 19, Page 1152-, Year 2012 |
Publish date | May 30, 2012 (structure data deposition date) |
![]() | Busschots, K. / Lopez-Garcia, L.A. / Lammi, C. / Stroba, A. / Zeuzem, S. / Piiper, A. / Alzari, P.M. / Neimanis, S. / Arencibia, J.M. / Engel, M. ...Busschots, K. / Lopez-Garcia, L.A. / Lammi, C. / Stroba, A. / Zeuzem, S. / Piiper, A. / Alzari, P.M. / Neimanis, S. / Arencibia, J.M. / Engel, M. / Schulze, J.O. / Biondi, R.M. |
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Methods | X-ray diffraction |
Resolution | 1.43 - 1.68 Å |
Structure data | ![]() PDB-4aw0: ![]() PDB-4aw1: |
Chemicals | ![]() ChemComp-ATP: ![]() ChemComp-MJF: ![]() ChemComp-DMS: ![]() ChemComp-MG: ![]() ChemComp-DTD: ![]() ChemComp-HOH: ![]() ChemComp-21O: ![]() ChemComp-MN: ![]() ChemComp-NA: ![]() ChemComp-CL: |
Source |
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![]() | TRANSFERASE / ALLOSTERIC REGULATION / ALLOSTERIC SITE / PHOSPHORYLATION / AGC PROTEIN KINASE |