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TitleMinimal conformational plasticity enables TCR cross-reactivity to different MHC class II heterodimers.
Journal, issue, pagesSci Rep, Vol. 2, Page 629-629, Year 2012
Publish dateAug 13, 2012 (structure data deposition date)
AuthorsHolland, C.J. / Rizkallah, P.J. / Vollers, S. / Calvo-Calle, J.M. / Madura, F. / Fuller, A. / Sewell, A.K. / Stern, L.J. / Godkin, A. / Cole, D.K.
External linksSci Rep / PubMed:22953050
MethodsX-ray diffraction
Resolution2.39 Å
Structure data

PDB-4gkz:
HA1.7, a MHC class II restricted TCR specific for haemagglutinin
Method: X-RAY DIFFRACTION / Resolution: 2.39 Å

Chemicals

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-SO4:
SULFATE ION

ChemComp-TAM:
TRIS(HYDROXYETHYL)AMINOMETHANE / pH buffer*YM

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / Major histocompatibility complex class II (pMHC-II) / T-cell / T-cell receptor (TCR) / influenza / HA1.7

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