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TitleT-cell Receptor-optimized Peptide Skewing of the T-cell Repertoire Can Enhance Antigen Targeting.
Journal, issue, pagesJ. Biol. Chem., Vol. 287, Page 37269-37281, Year 2012
Publish dateAug 13, 2012 (structure data deposition date)
AuthorsEkeruche-Makinde, J. / Clement, M. / Cole, D.K. / Edwards, E.S. / Ladell, K. / Miles, J.J. / Matthews, K.K. / Fuller, A. / Lloyd, K.A. / Madura, F. ...Ekeruche-Makinde, J. / Clement, M. / Cole, D.K. / Edwards, E.S. / Ladell, K. / Miles, J.J. / Matthews, K.K. / Fuller, A. / Lloyd, K.A. / Madura, F. / Dolton, G.M. / Pentier, J. / Lissina, A. / Gostick, E. / Baxter, T.K. / Baker, B.M. / Rizkallah, P.J. / Price, D.A. / Wooldridge, L. / Sewell, A.K.
External linksJ. Biol. Chem. / PubMed:22952231
MethodsX-ray diffraction
Resolution2.346 - 2.753 Å
Structure data

PDB-4gkn:
A2-MHC Complex carrying FATGIGIITV
Method: X-RAY DIFFRACTION / Resolution: 2.753 Å

PDB-4gks:
A2-MHC Complex carrying FLTGIGIITV
Method: X-RAY DIFFRACTION / Resolution: 2.346 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-GOL:
GLYCEROL

Source
  • homo sapiens (human)
  • synthetic construct (others)
KeywordsIMMUNE SYSTEM / Major Histocompatibility Complex / T-Cell Receptor / Immuno / Immunoglobulin / Recognition / MHC / TCR

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