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-Structure paper
Title | Mode of Action, In Vitro Activity, and In Vivo Efficacy of AFN-1252, a Selective Antistaphylococcal FabI Inhibitor. |
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Journal, issue, pages | Antimicrob. Agents Chemother., Vol. 56, Page 5865-5874, Year 2012 |
Publish date | Jun 26, 2012 (structure data deposition date) |
Authors | Kaplan, N. / Albert, M. / Awrey, D. / Bardouniotis, E. / Berman, J. / Clarke, T. / Dorsey, M. / Hafkin, B. / Ramnauth, J. / Romanov, V. ...Kaplan, N. / Albert, M. / Awrey, D. / Bardouniotis, E. / Berman, J. / Clarke, T. / Dorsey, M. / Hafkin, B. / Ramnauth, J. / Romanov, V. / Schmid, M.B. / Thalakada, R. / Yethon, J. / Pauls, H.W. |
External links | Antimicrob. Agents Chemother. / PubMed:22948878 |
Methods | X-ray diffraction |
Resolution | 1.8 Å |
Structure data | PDB-4fs3: |
Chemicals | ChemComp-0WD: ChemComp-0WE: ChemComp-HOH: |
Source |
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Keywords | OXIDOREDUCTASE / Rossmann Fold / short chain dehydrogenase / NADPH binding |