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Structure paper

TitleProcessive Steps in the Reverse Direction Require Uncoupling of the Lead Head Lever Arm of Myosin Vi.
Journal, issue, pagesMol. Cell, Vol. 48, Page 75-, Year 2012
Publish dateMar 19, 2012 (structure data deposition date)
AuthorsMenetrey, J. / Isabet, T. / Ropars, V. / Mukherjea, M. / Pylypenko, O. / Liu, X. / Perez, J. / Vachette, P. / Sweeney, H.L. / Houdusse, A.M.
External linksMol. Cell / PubMed:22940248
MethodsX-ray diffraction
Resolution2.25 - 2.6 Å
Structure data

PDB-4anj:
MYOSIN VI (MDinsert2-GFP fusion) PRE-POWERSTROKE STATE (MG.ADP.AlF4)
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

PDB-4e7s:
Myosin VI D23R I24R R569E (MD) pre-powerstroke state
Method: X-RAY DIFFRACTION / Resolution: 2.25 Å

PDB-4e7z:
Myosin VI (MD) pre-powerstroke state, P21 crystal form
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-ADP:
ADENOSINE-5'-DIPHOSPHATE / ADP, energy-carrying molecule*YM

ChemComp-MG:
Unknown entry

ChemComp-ALF:
TETRAFLUOROALUMINATE ION

ChemComp-CA:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-VO4:
VANADATE ION

ChemComp-GOL:
GLYCEROL

ChemComp-PO4:
PHOSPHATE ION

Source
  • sus scrofa (pig)
  • aequorea victoria (jellyfish)
  • drosophila melanogaster (fruit fly)
KeywordsMOTOR PROTEIN/METAL-BINDNG PROTEIN / MOTOR PROTEIN-METAL-BINDNG PROTEIN COMPLEX / MOLECULAR MOTOR / METAL-BINDING PROTEIN / TRANSITION STATE / PRE-POWERSTROKE STATE / GFP FUSION / MOTOR PROTEIN / myosin

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