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TitleThe M-T hook structure is critical for design of HIV-1 fusion inhibitors.
Journal, issue, pagesJ. Biol. Chem., Vol. 287, Page 34558-34568, Year 2012
Publish dateJun 2, 2012 (structure data deposition date)
AuthorsChong, H. / Yao, X. / Sun, J. / Qiu, Z. / Zhang, M. / Waltersperger, S. / Wang, M. / Cui, S. / He, Y.
External linksJ. Biol. Chem. / PubMed:22879603
MethodsX-ray diffraction
Resolution1.9 Å
Structure data

PDB-3vtp:
HIV fusion inhibitor MT-C34
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • human immunodeficiency virus type 1
KeywordsVIRAL PROTEIN/ANTIVIRAL PROTEIN / 6-helix-bundle / M-T hook / fusion inhibitor / membrane fusion / VIRAL PROTEIN-ANTIVIRAL PROTEIN complex

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