EMDB/PDB/SASBDBから引用されている文献のデータベース

キーワード
構造解析手法	All X線回折 NMR 電子顕微鏡小角散乱中性子線回折線維回折粉末回折赤外分光 EPR FRET 理論モデルハイブリッド
著者・登録者
ジャーナル
IF	>30 >20 >10 >5 all

タイトル	Structural Analysis of Specific Metal Chelating Inhibitor Binding to the Endonuclease Domain of Influenza Ph1N1 (2009) Polymerase.
ジャーナル・号・ページ	Plos Pathog., Vol. 8, Page 2831-, Year 2012
掲載日	2012年5月25日 (構造データの登録日)
著者	Kowalinski, E. / Zubieta, C. / Wolkerstorfer, A. / Szolar, O.H. / Ruigrok, R.W. / Cusack, S.
リンク	Plos Pathog. / PubMed:22876177
手法	X線回折
解像度	1.87 - 2.6 Å
構造データ	PDB-4avg: Influenza strain pH1N1 2009 polymerase subunit PA endonuclease in complex with diketo compound 2 手法: X-RAY DIFFRACTION / 解像度: 2.2 Å PDB-4avl: Influenza strain pH1N1 2009 polymerase subunit PA endonuclease in complex with dTMP 手法: X-RAY DIFFRACTION / 解像度: 1.87 Å PDB-4avq: Influenza strain pH1N1 2009 polymerase subunit PA endonuclease 手法: X-RAY DIFFRACTION / 解像度: 2.1 Å PDB-4awf: Influenza strain pH1N1 2009 polymerase subunit PA endonuclease in complex with 2 4-dioxo-4-phenylbutanoic acid DPBA 手法: X-RAY DIFFRACTION / 解像度: 2.3 Å PDB-4awg: Influenza strain pH1N1 2009 polymerase subunit PA endonuclease in complex with diketo compound 3 手法: X-RAY DIFFRACTION / 解像度: 2.6 Å PDB-4awh: Influenza strain pH1N1 2009 polymerase subunit PA endonuclease in complex with rUMP 手法: X-RAY DIFFRACTION / 解像度: 2.05 Å PDB-4awk: Influenza strain pH1N1 2009 polymerase subunit PA endonuclease in complex with diketo compound 1 手法: X-RAY DIFFRACTION / 解像度: 1.9 Å PDB-4awm: Influenza strain pH1N1 2009 polymerase subunit PA endonuclease in complex with (-)-epigallocatechin gallate from green tea 手法: X-RAY DIFFRACTION / 解像度: 2.6 Å
化合物	ChemComp-SL6: (Z)-4-[4-[(4-chlorophenyl)methyl]-1-(cyclohexylmethyl)piperidin-4-yl]-2-oxidanyl-4-oxidanylidene-but-2-enoic acid / (2Z)-2-ヒドロキシ-4-オキソ-4-[4-(4-クロロベンジル)-1-(シクロヘキシルメチル)ピペリジン-4-イ(以下略) ChemComp-MN: Unknown entry ChemComp-HOH: WATER ChemComp-TMP: THYMIDINE-5'-PHOSPHATE / TMP ChemComp-MG: Unknown entry / マグネシウムジカチオン ChemComp-XI7: 2-4-DIOXO-4-PHENYLBUTANOIC ACID / 2,4-ジオキソ-4-フェニル酪酸 ChemComp-SO4: SULFATE ION / 硫酸ジアニオン ChemComp-CI3: (2Z)-4-[(3S)-1-benzyl-3-(4-chlorobenzyl)piperidin-3-yl]-2-hydroxy-4-oxobut-2-enoic acid ChemComp-U5P: URIDINE-5'-MONOPHOSPHATE / UMP ChemComp-CI1: (2Z)-4-[(3S)-1-(benzylsulfonyl)-3-(4-chlorobenzyl)piperidin-3-yl]-2-hydroxy-4-oxobut-2-enoic acid ChemComp-KDH: (2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl 3,4,5-trihydroxybenzoate / (-)-エピガロカテキンガラ-ト
由来	influenza a virus (A型インフルエンザウイルス) influenza virus (インフルエンザウイルス)
キーワード	HYDROLASE/INHIBITOR / HYDROLASE-INHIBITOR COMPLEX / HYDROLASE / MANGANESE-DEPENDENT / ENDONUCLEASE / PD...D-E...K SUPERFAMILY