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TitleMolecular structure of human GM-CSF in complex with a disease-associated anti-human GM-CSF autoantibody and its potential biological implications.
Journal, issue, pagesBiochem. J., Vol. 447, Page 205-215, Year 2012
Publish dateApr 16, 2012 (structure data deposition date)
AuthorsBlech, M. / Seeliger, D. / Kistler, B. / Bauer, M.M. / Hafner, M. / Horer, S. / Zeeb, M. / Nar, H. / Park, J.E.
External linksBiochem. J. / PubMed:22839360
MethodsX-ray diffraction
Resolution1.97 Å
Structure data

PDB-4eow:
Crystal structure of a disease-associated anti-human GM-CSF autoantibody MB007
Method: X-RAY DIFFRACTION / Resolution: 1.97 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / Immunsystem / alpha-helical stretch in CDR3-H / protein-docking / Immunoglobulin IgG1 (lambda) / autoantibody causing PAP / GM-CSF

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