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Structure paper

TitleSubstrate binds in the S1 site of the F253A mutant of LeuT, a neurotransmitter sodium symporter homologue.
Journal, issue, pagesEmbo Rep., Vol. 13, Page 861-866, Year 2012
Publish dateJul 3, 2012 (structure data deposition date)
AuthorsWang, H. / Gouaux, E.
External linksEmbo Rep. / PubMed:22836580
MethodsX-ray diffraction
Resolution2.601 - 3 Å
Structure data

PDB-4fxz:
Crystal structure of LeuT-F253A bound to L-leucine from lipid bicelles
Method: X-RAY DIFFRACTION / Resolution: 2.601 Å

PDB-4fy0:
Crystal structure of LeuT-F253A bound to L-selenomethionine from lipid bicelles
Method: X-RAY DIFFRACTION / Resolution: 3 Å

Chemicals

ChemComp-LEU:
LEUCINE

ChemComp-NA:
Unknown entry

ChemComp-ACT:
ACETATE ION

ChemComp-UND:
UNDECANE

ChemComp-HOH:
WATER

ChemComp-MSE:
SELENOMETHIONINE

Source
  • aquifex aeolicus (bacteria)
KeywordsTRANSPORT PROTEIN / amino acid transporter

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