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TitleAntibiotic optimization and chemical structure stabilization of thiomuracin A.
Journal, issue, pagesJ. Med. Chem., Vol. 55, Page 6934-6941, Year 2012
Publish dateJul 17, 2012 (structure data deposition date)
AuthorsLaMarche, M.J. / Leeds, J.A. / Dzink-Fox, J. / Gangl, E. / Krastel, P. / Neckermann, G. / Palestrant, D. / Patane, M.A. / Rann, E.M. / Tiamfook, S. / Yu, D.
External linksJ. Med. Chem. / PubMed:22812377
MethodsX-ray diffraction
Resolution2.3 Å
Structure data

PDB-4g5g:
ef-tu (Escherichia coli) complexed with nvp-ldu796
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-GDP:
GUANOSINE-5'-DIPHOSPHATE / GDP, energy-carrying molecule*YM

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • escherichia coli (E. coli)
  • synthetic construct (others)
Keywordstranslation/antibiotic / ELONGATION FACTOR / translation-antibiotic complex

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