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-Structure paper
Title | Crystal structure of 12-lipoxygenase catalytic-domain-inhibitor complex identifies a substrate-binding channel for catalysis. |
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Journal, issue, pages | Structure, Vol. 20, Page 1490-1497, Year 2012 |
Publish date | Apr 1, 2011 (structure data deposition date) |
Authors | Xu, S. / Mueser, T.C. / Marnett, L.J. / Funk, M.O. |
External links | Structure / PubMed:22795085 |
Methods | X-ray diffraction |
Resolution | 1.892 Å |
Structure data | PDB-3rde: |
Chemicals | ChemComp-K: ChemComp-FE2: ChemComp-OYP: ChemComp-HOH: |
Source |
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Keywords | OXIDOREDUCTASE/OXIDOREDUCTASE inhibitor / lipoxygenase / C-terminal domain / protein-inhibitor complex / 4-(2-oxapentadeca-4-yne)phenylpropanoic acid / lipoxygenase catalytic domain / dioxygenase / Fe / leukocyte / OXIDOREDUCTASE-OXIDOREDUCTASE inhibitor complex |