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Structure paper

TitleA Novel Allosteric Inhibitor of Macrophage Migration Inhibitory Factor (MIF).
Journal, issue, pagesJ. Biol. Chem., Vol. 287, Page 30653-30663, Year 2012
Publish dateSep 29, 2011 (structure data deposition date)
AuthorsBai, F. / Asojo, O.A. / Cirillo, P. / Ciustea, M. / Ledizet, M. / Aristoff, P.A. / Leng, L. / Koski, R.A. / Powell, T.J. / Bucala, R. / Anthony, K.G.
External linksJ. Biol. Chem. / PubMed:22782901
MethodsX-ray diffraction
Resolution1.9 Å
Structure data

PDB-3u18:
Chicago Sky Blue 6B, A Novel Inhibitor for Macrophage Migration Inhibitory Factor
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

Chemicals

ChemComp-Y0X:
6,6'-[(3,3'-dimethoxybiphenyl-4,4'-diyl)di(E)diazene-2,1-diyl]bis(4-amino-5-hydroxynaphthalene-1,3-disulfonic acid)

ChemComp-IPA:
ISOPROPYL ALCOHOL / alkaloid*YM

ChemComp-GOL:
GLYCEROL

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-NA:
Unknown entry

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsCYTOKINE

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