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Structure paper

TitleStructure and proposed mechanism for the pH-sensing Helicobacter pylori chemoreceptor TlpB.
Journal, issue, pagesStructure, Vol. 20, Page 1177-1188, Year 2012
Publish dateOct 23, 2011 (structure data deposition date)
AuthorsGoers Sweeney, E. / Henderson, J.N. / Goers, J. / Wreden, C. / Hicks, K.G. / Foster, J.K. / Parthasarathy, R. / Remington, S.J. / Guillemin, K.
External linksStructure / PubMed:22705207
MethodsX-ray diffraction
Resolution1.38 - 1.9 Å
Structure data

PDB-3ub6:
Periplasmic portion of the Helicobacter pylori chemoreceptor TlpB with urea bound
Method: X-RAY DIFFRACTION / Resolution: 1.38 Å

PDB-3ub7:
Periplasmic portion of the Helicobacter pylori chemoreceptor TlpB with acetamide bound
Method: X-RAY DIFFRACTION / Resolution: 1.4 Å

PDB-3ub8:
Periplasmic portion of the Helicobacter pylori chemoreceptor TlpB with formamide bound
Method: X-RAY DIFFRACTION / Resolution: 1.42 Å

PDB-3ub9:
Periplasmic portion of the Helicobacter pylori chemoreceptor TlpB with hydroxyurea bound
Method: X-RAY DIFFRACTION / Resolution: 1.42 Å

PDB-4exo:
Revised, rerefined crystal structure of PDB entry 2QHK, methyl accepting chemotaxis protein
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

Chemicals

ChemComp-URE:
UREA

ChemComp-SO4:
SULFATE ION

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

ChemComp-ACM:
ACETAMIDE

ChemComp-ARF:
FORMAMIDE

ChemComp-NHY:
N-HYDROXYUREA / medication*YM

ChemComp-PYR:
PYRUVIC ACID

Source
  • helicobacter pylori (bacteria)
  • vibrio parahaemolyticus (bacteria)
KeywordsMEMBRANE PROTEIN / homodimer / four-helix bundle / PAS domain / SIGNALING PROTEIN / chemotaxis receptor / four helix bundle / methyl accepting chemotaxis receptor / periplasmic domain

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